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See 5 for more information on attributes 2 Build the business object Class Library project The InventoryDate property no longer appears in the Data Sources window

[w~M)(q)Mn (k,p-p q) +w~N)(q)Nn (k,p-p q)]

(9.3.63)

where w~M)(q) and w~N)(q) are the final exciting field coefficients. The exciting field of cylinder p is

Furthermore, in terms of the mix of in vestment during the same period, the percentage of R&D monies spent on the development of new blockbuster drugs was about 80 percent world wide, with the remainder spent on new formulations and other modi ca tions of existing drugs Figure 29 illustrates how the rate of investment inside the United States has increased exponentially since about 1995 Furthermore, accord ing to gures from PhRMA and the European Federation of Pharmaceuti cal Industries and Associations (EFPIA), since mid-1990s, the rate of growth in R&D investment in the United States has been double that of investment in Europe, the former global leader in pharmaceutical research and development This increased concentration of R&D investment in the United States is re ected in sales.

Eex(P) =

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For the Purchase Tracker sample application: Open the Product class in the Code Editor Modify the InventoryDate property so that it is hidden from the Data Sources window as detailed in this section Build the business object Class Library project (PTBO) The InventoryDate no longer appears in the Data Sources window

[w~~)(P)RgMnl (k,p-pp) +w~!'j)(p)RgNnl (k,p-pp)]

(9.3.64)

The scattered field from particle pis,

ES(P)

The Data Sources window de nes all the sources of data for the user interface When using object binding, add a data source for every business object class that you plan to use for binding And don t forget to rebuild your business object Class Library project after every property change to ensure that the changes are re ected in the Data Sources window

[T~~1)w~~)(P)Mnl (k,p-pp) +T~~)w~!'j)(P)Nnl (k,p-pp)]

(9.3.65)

where T~;"f) and T~;.f) are the T -matrix coefficients. To obtain equations for the exciting field coefficents from the Foldy-Lax multiple scattering equations, we need the translational addition theorem of

For example, of the top ten drugs world wide in 2002, eight were developed in the United States and two were from Europe As shown in Figure 210, about a third of investment in R&D is fo cused on the earliest stages of the drug development process In 2000, PhRMA member companies invested about $65 billion or 306 percent of their total R&D budget on screening, lead development, and preclinical tri als Phase I, II, and III clinical trials accounted for another $55 billion, or just over a quarter of the total R&D investment The investment in Phase IV clinical trials was relatively small at $18 billion, or 88 percent of the to tal expenditure for R&D In addition, $06 billion was spent acquiring reg ulatory approval from the FDA An additional $1.

(l) H n'

7

(9.3.66)

makes with the x-axis (see (9.3.67) (9.3.68)

P- pi = P- Po - (pi - Po)

(l) H n'

\p - Pol) ein~H~~n'

.

Ip' - Pol) e-i(n-n')</>-;;T;;;;"

(9.3.69)

5 billion, or 7 percent of the total R&D, was spent on process development for manufacturing and.

(9.3.71)

N n, (k,p-p p)

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